Relationship Between Melatonin and CSC Discovered by UWF SS-OCTA!

2026-08-11 16:36

Research published in International Ophthalmology investigates changes in melatonin secretion levels and their association with choroidal vasculature parameters in patients with central serous chorioretinopathy (CSC), using a UWF full-range SS-OCTA (#Bmizar, TowardPi).

This study revealed that CSC patients had lower levels of urinary 6-sulfatoxymelatonin (6-SMT). Normalized 6-SMT was found to have negative correlations with choroidal vascular volume (CVV), choroidal vascularity index (CVI), and choroidal thickness (CT), suggesting that decreased melatonin secretion might be a risk factor for CSC.

This research was authored by Dr. Kun Xu and the team of Dr. Shanshan Yu and Prof. Xiaoling Liang from Zhongshan Ophthalmic Center.

Link to original text:

https://link.springer.com/article/10.1007/s10792-025-03838-2

#ophthalmology #SSOCT #medicaldevices

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