Advanced Imaging of Corneal Neovascularization with Full-Range SS AS-OCTA

Research published in the British Journal of Ophthalmology explored the clinical application of a novel swept-source anterior segment OCT angiography (AS-OCTA) system for imaging corneal neovascularisation (CoNV), assessing limbal vasculature, and detecting short-term vascular changes following pharmacologic vasoconstriction.

Compared with normal controls, eyes with CoNV exhibited significantly higher total and deep corneal FlowArea. Following pharmacologic vasoconstriction, a significant reduction in FlowArea was observed in the total and deep corneal layers of CoNV eyes, as well as in the limbal region of both CoNV eyes and control eyes.

A 400 kHz swept-source OCTA system (BMizar, TowardPi Medical) was used in this study to acquire high-resolution, depth-resolved OCTA images of the full corneal and limbal regions within a single scan. This capability offers potential value for improving diagnosis, monitoring treatment response, and guiding personalized management strategies.

This study was authored by Dr. Luca Lucchino and colleagues from the team led by Prof. Sabrina Vaccaro, representing the University of Brescia, ASST Spedali Civili di Brescia, the University of Rome La Sapienza, and the University of Bologna, Italy.

Link to the original article: https://bjo.bmj.com/content/110/1/25