CLR/LT—A Novel Preoperative Index for Predicting In-the-Bag IOL Position Measured Full-Range SS AS-OCT

Research published in the American Journal of Ophthalmology investigated whether a novel preoperative biometric index integrating lens geometry—lens thickness (LT) and the relative position of the capsular bag, expressed as crystalline lens rise (CLR)—could predict the postoperative in-the-bag intraocular lens (IOL) position proportion coefficient and, subsequently, the final IOL position using full-range swept-source anterior segment (AS) OCT.

Additional parameters, including LT, CLR, angle recess width (ARW), IOL thickness (TIOL), and 1/2 TLAW (half the IOL thickness plus the distance from the IOL anterior surface to the ARW plane), were measured using 100 kHz swept-source OCT (Yalkaid, TowardPi).

The correlations between these parameters and the in-the-bag IOL position proportion coefficient were analyzed. The accuracy of IOL position calculations using the estimated coefficient was compared with conventional vergence formulas. This study highlights the complex dynamics of the anterior segment and the value of direct measurement of lens anatomical factors. The CLR/LT ratio demonstrated a strong association with the postoperative IOL position proportion coefficient (ρ = 0.750). Compared with standard formulas, calculating IOL position using the predicted IOL position proportion coefficient significantly improved prediction accuracy, particularly in eyes with atypical axial length (AL).

This research was authored by Dr. Jianxia Fang, Dr. Xinyu Ma, and colleagues from the team led by Prof. Wen Xu, Eye Center, The Second Affiliated Hospital of Zhejiang University.

Link to the original article:
https://www.ajo.com/article/S0002-9394(25)00414-3/fulltext