
Quantitative imaging Biomarkers of PCV by Using Full Range SS-OCTA!
- Categories:Academy
- Time of issue:2025-01-21 19:01
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(Summary description)Quantitative imaging biomarkers of PCV by using full range SS-OCTA! Research recently published in <Microvascular Research> evaluated quantitative metrics of neovascularization lesions and choroidal vascular in PCV eyes, and investigated the relationship between imaging biomarkers and anti-VEGF treatment outcome by using full range SS-OCTA. The results indicated that a higher number of endpoints and lower average vessel length of PCV lesions were correlated with high shrinkage of vessel area after anti-VEGF treatment, and a lower subfoveal choroidal thickness was correlated with good morphological response to anti-VEGF. Therefore, ‘quantitative metrics of neovascularization lesions and choroidal characteristics using SS-OCTA had the potential to be imaging biomarkers for predicting the response to anti-VEGF treatment’. A 400kHz speed swept source OCTA (BMizar, TowardPi Medical) was used in this study to acquire high-resolution image of neovascularization and choroidal vessels with built-in precise segmentation algorithm and choroid angiography algorithm. Choroid quantitative parameters such as subfoveal choroidal thickness (SFCT) and choroidal vascularity index (CVI) are available on device. Further quantitative metrics based on high-resolution OCTA images, including total vessel length (TVL), average vessel length (AVL), junction density (JD), total number of endpoints (TNE), and mean lacunarity (ML), were evaluated in this research. This research is authored by Dr. Yue Zhang, etc. team of Prof. Xiaobing Yu, from Beijing Hospital. Link to original text: https://www.sciencedirect.com/science/article/abs/pii/S0026286224001080
Quantitative imaging Biomarkers of PCV by Using Full Range SS-OCTA!
(Summary description)Quantitative imaging biomarkers of PCV by using full range SS-OCTA!
Research recently published in <Microvascular Research> evaluated quantitative metrics of neovascularization lesions and choroidal vascular in PCV eyes, and investigated the relationship between imaging biomarkers and anti-VEGF treatment outcome by using full range SS-OCTA.
The results indicated that a higher number of endpoints and lower average vessel length of PCV lesions were correlated with high shrinkage of vessel area after anti-VEGF treatment, and a lower subfoveal choroidal thickness was correlated with good morphological response to anti-VEGF. Therefore, ‘quantitative metrics of neovascularization lesions and choroidal characteristics using SS-OCTA had the potential to be imaging biomarkers for predicting the response to anti-VEGF treatment’.
A 400kHz speed swept source OCTA (BMizar, TowardPi Medical) was used in this study to acquire high-resolution image of neovascularization and choroidal vessels with built-in precise segmentation algorithm and choroid angiography algorithm. Choroid quantitative parameters such as subfoveal choroidal thickness (SFCT) and choroidal vascularity index (CVI) are available on device. Further quantitative metrics based on high-resolution OCTA images, including total vessel length (TVL), average vessel length (AVL), junction density (JD), total number of endpoints (TNE), and mean lacunarity (ML), were evaluated in this research.
This research is authored by Dr. Yue Zhang, etc. team of Prof. Xiaobing Yu, from Beijing Hospital.
Link to original text:
https://www.sciencedirect.com/science/article/abs/pii/S0026286224001080
- Categories:Academy
- Time of issue:2025-01-21 19:01
- Views:
Quantitative imaging biomarkers of PCV by using full range SS-OCTA!
Research recently published in <Microvascular Research> evaluated quantitative metrics of neovascularization lesions and choroidal vascular in PCV eyes, and investigated the relationship between imaging biomarkers and anti-VEGF treatment outcome by using full range SS-OCTA.
The results indicated that a higher number of endpoints and lower average vessel length of PCV lesions were correlated with high shrinkage of vessel area after anti-VEGF treatment, and a lower subfoveal choroidal thickness was correlated with good morphological response to anti-VEGF. Therefore, ‘quantitative metrics of neovascularization lesions and choroidal characteristics using SS-OCTA had the potential to be imaging biomarkers for predicting the response to anti-VEGF treatment’.
A 400kHz speed swept source OCTA (BMizar, TowardPi Medical) was used in this study to acquire high-resolution image of neovascularization and choroidal vessels with built-in precise segmentation algorithm and choroid angiography algorithm. Choroid quantitative parameters such as subfoveal choroidal thickness (SFCT) and choroidal vascularity index (CVI) are available on device. Further quantitative metrics based on high-resolution OCTA images, including total vessel length (TVL), average vessel length (AVL), junction density (JD), total number of endpoints (TNE), and mean lacunarity (ML), were evaluated in this research.
This research is authored by Dr. Yue Zhang, etc. team of Prof. Xiaobing Yu, from Beijing Hospital.
Link to original text:
https://www.sciencedirect.com/science/article/abs/pii/S0026286224001080
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