OCTA users might have concern about the reliability of blood flow quantification from large size scan. After all, quantification was provided for small size mostly in the past, due to resolution limitation of large scan. Not to mention 120° choroid vessel (ChV) density of Sattler’s and Haller’s layers from TowardPi, something so new that we haven’t tried before.

Please note that the resolution of TowardPi 24mm (120°) OCTA is as same as 6x6mm in the past. Recent published research evaluated the repeatability of vessel density and structural thickness from TowardPi OCTA quantification. The result is very promising.

Intra-class correlation coefficients (ICCs) ranging of ChV Vessel densities and the thicknesses in peripheral regions are 0.813 to 1.000. ICCs of retinal thickness and vessel density reached 0.916 and 1.000!

In addition to the new finding of myopic fundus in choroid and peripheral (see previous post), research also agrees with previous study that shows a strong correlation between the vascular perfusing parameters and retinal thickness at the macular region, “That demonstrated the new ultrawide-field OCTA system can provide novel information without losing the sensitivity and resolution at the macula”.

How many ideas will you have when you own such novel and powerful 400KHz SS-OCT for your research in the future?

< Advanced UWF OCTA identifies previously undetectable changes in biomechanics-related parameters in nonpathological myopic fundus> published on <Frontiers in Bioengineering and Biotechnology>.

Author: Dr. Weiran Zhang, and Team of Prof. Zhiqing Li, from Tianjin Medical University Eye Hospital, etc.

Full text open access:

https://www.frontiersin.org/.../fbioe.2022.920197/full

https://doi.org/10.3389/fbioe.2022.920197