A 54-year-old female patient with painless vision loss in her right eye was found to have a large circular yellowish-white intraocular mass with little pigmentation as shown in the color fundus image (A). Ophthalmic ultrasound showed an intraocular mushroom-shaped choroidal mass with abundant blood flow. MRI revealed corresponding intraocular, oval, T1-isointense, and T2-hyperintense mass (C). UWF full-range OCTA clearly revealed vascular information in the tumor. A double circulation pattern between retinal and tumor vessels was shown by novel 3D OCTA, corresponding to the result of fluorescein fundus angiography. A diagnosis of amelanotic choroidal melanoma was confirmed by histopathological examination.

A 400kHz speed full-range swept-source OCTA (BMizar, TowardPi Medical) was used in this case to acquire a high-resolution OCTA image of the large intraocular tumor. 3D reconstruction of structure and flow are both available on the device which can provide an insight into the circulation pattern of diseases.

This case was published in <Ophthalmology>, authored by Dr. Zhihao Jiang and Dr. Xintong Jiang, team of Prof. Jie Hu, from Zhongshan Ophthalmic Center, Sun Yat-sen University.

Link to the article: https://www.aaojournal.org/article/S0161-6420(24)00426-3/fulltext