A new study was published in the “Translational Vision Science & Technology”. The proportion of the choroidal vortex vein drainage system (VV%), defined as the ratio of the drainage area in each quadrant to the area of the entire post-equatorial fundus, was evaluated in Central Serous Chorioretinopathy (CSC) patients. The CSC group had a significantly higher proportion of the choroidal vortex vein drainage system in the supratemporal (ST) quadrant than the control group.

Fig1.  A&B showed a different VV% between the healthy eye and the CSC eye. The macular leakage rate was significantly higher in the ST quadrant after colocating the leakage points in FA with the En Face OCT as shown in Figure E.

Interestingly, for CSC eyes, the ST drainage quadrant had the largest CVV and CSV as well as the thickest choroidal layer among the four drainage quadrants as shown in Fig2. (A)-(J), indicating that the ST quadrant contributes to the major choroid drainage and may be the preferential drainage route of the submacular choroid in CSC.

All these findings indicated that the greatest choroid blood flow occurred in the temporal quadrants, especially the ST drainage area. ‘The asymmetric choroidal vortex vein drainage system may play a key role in the imbalanced distribution of choroidal venous flow!’

A 400kHz speed swept-source OCTA BMizar was used in this study to achieve 24mmx20mm choroid OCTA. Five 24mmx20mm images were automatically montaged into a UWF choroid image (>200 degrees).

This study was authored by Dr. Zhonghua Luo etc, a team of Prof. Xiaoling Liang, from Zhongshan Ophthalmic Center, Sun Yat-Sen University.

Full text: https://tvst.arvojournals.org/article.aspx?articleid=2792778