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A Thicker Sclera Was Found In SLE Patients Even Without Scleritis by Using SS-OCT

A thicker sclera was found by SS-OCT in SLE patients even without scleritis. A new study assessing scleral thickness (Nasal/Temporal scleral thickness 1mm, 2mm, 3mm, 6mm from the scleral spur; as shown) between SLE patients without clinically evident scleritis and episcleritis and healthy control was recently published in "Frontiers in Immunology" by using a 400KHz SS-OCT BMizar from TowardPi Medical.

Peripheral CVI Decreased in T2DM Patients Without DR, a New Study Using 400kHz Swept-Source OCTA

A new study on early choroidal lesions in NDR patients was published in "Photodiagnosis and Photodynamic Therapy". Choroidal parameters including the thickness and VD of the choroid was compared between NDR patients (T2DM without DR) and normal control. Reduced choroidal thickness and CVI in the peripheral choroid indicated that general atrophy in the peripheral large and medium choroidal vessels (LMCV) was more significant in the preclinical or early DR patients! Meanwhile, compared with 2D choroidal vessel density, 3D indicators (such as CVI) were more sensitive for detecting diabetic choroidopathy!

Coral in the Conjunctiva Captured with Swept-Source OCTA

A 28-year-old female with a 3-year history of tumor in the left eye. An isolated pink tumor was observed in the conjunctiva with an associated large vessel. . Pathological examination revealed conjunctival papilloma. Swept-source OCTA, Yalkaid from TowardPi Medical, was used in this case.

The Effect of Alcohol Consumption on the Choroidal and Retinal Microvasculature

A new study exploring the impact of acute, heavy alcohol consumption on the choroidal and retinal microvasculature was published in "Microvascular Research", elucidating notable choroidal arteriolovenular constriction, represented by reduced CV and CVV, and dilation of choroidal capillaries, represented by increased CCD, after acute alcohol consumption. 17 healthy volunteers aged 20 to 30 years consumed three different liquids (spirits, wine and water) in random sequence on three separate days.

Asymmetric Vortex Vein Drainage System Plays a Key Role in CSC

A new study was published in the “Translational Vision Science & Technology”. The proportion of the choroidal vortex vein drainage system (VV%), defined as the ratio of the drainage area in each quadrant to the area of the entire post-equatorial fundus, was evaluated in Central Serous Chorioretinopathy (CSC) patients. The CSC group had a significantly higher proportion of the choroidal vortex vein drainage system in the supratemporal (ST) quadrant than the control group.

Major Depressive Disorder Exhibits Lower Choroidal Vessel Density

A new study, published in the Journal of Affective Disorders, compared choroidal vessel density with healthy controls (HCs) and found it to be lower in MDD patients. This suggests abnormalities in choroidal vasculature in individuals with MDD. Utilizing UWF-OCTA and automatic quantification in the choroidal vessel layer, the study revealed significantly lower supranasal and temporal CVV, temporal CVI, and supranasal and temporal CSV in MDD patients. Enclosed OCTA images illustrated the lower CVV in MDD compared to normal controls.

CRAO Recanalization Recorded by 400K Speed SS-OCTA

Race against time! CRAO recanalization recorded by 400K speed SS-OCTA! A 66-year-old female complained of right eye rapid vision loss in one hour. Typical diffuse retinal whitening with a cherry-red spot in the macula. UWF-OCTA showed non-perfusion in the entire retina due to central retinal arterial occlusion. Following the OCTA scan the process of recanalization. VA improved from NLP to 0.1.

Spontaneous Carotid-Cavernous Fistula

Spontaneous Carotid-Cavernous Fistula. Ultra-widefield OCTA with corresponding choroidal thickness map shows dilated corkscrew alterations of the choroidal vasculature. Published in Pictures & Perspectives and posted by its official X (Twitter).

 New Findings in Chicks Study with TowardPi Wide-FIeld Swept-Source OCT

Does defocus induce spatial changes in choroidal thickness? New findings in chicks study with TowardPi SS-OCT. In the negative lens group, the global choroidal thickness (ChT) of the treated eyes was significantly less than that of the fellow eyes on day 7, but thicker on day 21. In the positive lens group, the ChT of both eyes increased on day 7 and decreased on day 21. These results provide evidence for regionally asymmetric characteristics of the choroidal response to visual cues and insights into the underlying mechanisms of emmetropization.

Massive Hemorrhagic Retinal Pigment Epithelial Detachment (PED) Secondary to Polypoidal Choroidal Vasculopathy (PCV)

Massive hemorrhagic retinal pigment epithelial detachment (PED) secondary to polypoidal choroidal vasculopathy (PCV) , pre and post surgery. Fig1. 24mm SS-OCT image before surgery demonstrated the subretinal hemorrhage (green asterisk) and elevation of RPE temporal to the macula (yellow asterisk); Fig2. 24mm SS-OCT image taken 1 day after surgery proved flattening of PED, a double-layer sign, and choroidal excavation together with mild subretinal fluid in the macula. Patient underwent PPV combined with subretinal injection of tPA, intravitreous injection of anti-VEGF medicine, and perfluoropropane tamponade.
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