• Categories：Gallery
• Time of issue：2025-02-12 14:18
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(Summary description)‘Ghost’ vessels in Retinitis pigmentosa revealed by UWF SS-OCTA！ A 48-year-old male patient who had suffered from night blindness and decreasing peripheral vision for 40 years was diagnosed as retinitis pigmentosa (RP). Typical pigment deposits (fig.1 red arrow) in the mid periphery were shown on the color fundus images in his both eyes. Hyper-autofluorescent rings at post pole around macula were revealed by autofluorescence imaging in both eyes correlating with the relatively preserved photoreceptor layer at macula while peripheral hypo-autofluorescent （fig.1 green arrow）was observed. Ultrawide field 24mm B-scan images showed thinning of the photoreceptor layers with loss of the ellipsoid zone and remaining RPE outside of macula while atrophy retina and RPE or even absence of RPE and the outer nuclear layer in the mid periphery. Intraretinal hyperreflective spots in the periphery could also be observed (fig.1 orange square). On the UWF full range SS-OCTA images, typical vascular features of RP including vessel narrowing and sclerosis, significative reduction of retinal vessels in the mid periphery and nonperfusion periphery were clearly revealed, correlating to the severely reduced retinal vessel density (fig.2). In fact, the remaining vessel walls of some occluded retinal vessels could still be seen on the En face images of deep retinal vessel layer (fig.2 purple arrow) together with large amount of pigment deposits (fig.2 red arrow). A 400kHz speed swept source OCTA (#BMizar, TowardPi Medical) was used in this case to capture ultrawide field 24mm x 20mm full range SS-OCTA images of vascular abnormalities and retinal degeneration of RP. Precise segmentation algorithm and flow quantifications are available on the device for disease assessment. Case courtesy of: Dr. Jieqiong Chen, team of Prof. Xiaodong Sun from Shanghai General Hospital. Editor: Dr. Chloe Li, TowardPi Medical